Rare Bleeding Disorders

Factor X Deficiency

Factor X deficiency affects about 1 in every 1 million people. It is equally likely to affect men and women.1

Common symptoms of factor X deficiency include1:

  • Nosebleeds
  • Easy bruising
  • Muscle and joint bleeds
  • Bleeding during or after surgery, injury, or dental procedures


No factor X concentrates are currently available, so fresh-frozen plasma (FFP) or prothrombin complex concentrate (PCC) containing factor X is typically used as treatment. Women with heavy periods who have factor X deficiency can be treated with birth control pills or antifibrinolytic drugs to promote clotting.


  1. What Are Rare Clotting Factor Deficiencies? Montreal, QC: World Federation of Hemophilia; 2009.